Statins & Combination Statins and combination drugs are the most commonly prescribed lipid-lowering medications for managing high cholesterol levels. They work by reducing the production of cholesterol in the liver and are widely used to prevent cardiovascular diseases.
PCSK9 Inhibitors PCSK9 inhibitors are a newer class of lipid-lowering drugs that help lower LDL cholesterol levels by blocking the PCSK9 protein. These drugs are typically prescribed for patients with familial hypercholesterolemia or those who cannot tolerate statins.
Bile Acid Sequestrants Bile acid sequestrants are medications that bind to bile acids in the intestine, preventing them from being reabsorbed into the bloodstream. This process helps lower LDL cholesterol levels and is often recommended for patients with high cholesterol levels.
Fibrates Fibrates are lipid-lowering drugs that help reduce triglyceride levels and increase HDL cholesterol levels. They are commonly prescribed for patients with high triglycerides or combined hyperlipidemia.
Cholesterol Absorption Inhibitors Cholesterol absorption inhibitors work by blocking the absorption of dietary cholesterol in the intestine. These drugs are often used in combination with statins to further lower LDL cholesterol levels.
Others Other lipid-lowering drugs include niacin, Omega-3 fatty acids, and ezetimibe, among others. These medications may be prescribed for patients who do not respond to or cannot tolerate other lipid-lowering drugs.
Indication:
Hypercholesterolemia Hypercholesterolemia is a common indication for lipid-lowering drugs, characterized by high levels of LDL cholesterol in the blood. Statins, PCSK9 inhibitors, and bile acid sequestrants are often prescribed to manage this condition.
Coronary Artery Disease Patients with coronary artery disease often require lipid-lowering medications to reduce their risk of cardiovascular events. Statins are the first-line treatment for these patients, with PCSK9 inhibitors and fibrates also being used in some cases.
High Triglycerides High triglyceride levels are a risk factor for cardiovascular disease and may require treatment with fibrates, niacin, Omega-3 fatty acids, or other lipid-lowering drugs. These medications help lower triglyceride levels and reduce the risk of heart disease.
Distribution Channel:
Retail Pharmacies Retail pharmacies are the most common distribution channel for lipid-lowering drugs, providing easy access for patients to fill their prescriptions. Patients can consult with pharmacists and access medication information at these locations.
Hospital Pharmacies Hospital pharmacies also play a significant role in distributing lipid-lowering drugs to patients who are hospitalized or receiving treatment in a healthcare facility. These pharmacies ensure that patients receive the necessary medications during their stay.
Online Pharmacies Online pharmacies offer a convenient option for patients to order and refill their lipid-lowering medications from the comfort of their homes. This distribution channel provides a discreet way for patients to access their prescribed medications and manage their cholesterol levels.